机械血栓切除术与急性缺血性中风中的静脉血栓溶解的成本效益:系统性审查

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Nasim Jaberi¹, Mohammad Alimoradnori¹, Aghdas Souresrafil²

¹Department of Health Economics, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran.

Expert review of pharmacoeconomics & outcomes research

|December 23, 2025

概括

机械血栓切除术 (MT) 是全球急性缺血性中风 (AIS) 的一个经济有效的治疗方法. 本综述综合了证据,并为评估MT提供了一个评估MT框架.

科学领域:

卫生经济学卫生经济学
神经学神经学
干预心脏病学干预心脏病学

背景情况:

机械血栓切除术 (MT) 是急性缺血性中风 (AIS) 的关键治疗方法.
与静脉血栓溶解 (IVT) 相比,MT的整体成本效益需要合成.
卫生系统的变化需要具体的环境经济评估.

研究的目的:

为AIS系统地审查和综合MT与IVT的经济评估.
开发一个框架来评估在不同的医疗保健环境中MT的成本效益.
确定影响MT成本效益的因素.

主要方法:

在四个数据库中按照PRISMA 2020指南进行系统的文献搜索.
使用健康经济研究质量 (QHES) 检查清单对经济评估的质量评估.
研究结果的定性综合,将增量成本效益比率 (ICER) 转换为2024美元,并根据收入水平,视角和数据来源对研究进行分类.

主要成果:

56项研究符合纳入标准,平均QHES得分为0.83,表明方法质量高.
在各种医疗保健环境中,MT表现出一致的成本效益或主导地位.
ICER变化的关键驱动因素包括设备成本,患者年龄,时间地平线,急性护理成本以及用于功能结果和实用权重的数据.

结论:

机械血栓切除术是急性缺血性中风的高价值干预措施.
成本效益取决于环境,突出了对本地化决策框架的需求.
未来的研究应该解决地理不平等问题,扩大来自低资源环境的证据,并整合现实世界的数据.

关键词:

对成本效益的分析.急性缺血性中风是急性缺血性中风.经济评估经济评价静脉内血栓溶解是一种静脉内血栓溶解.机械血栓切除术是一种机械血栓切除术.系统性审查系统性审查

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