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Updated: Jan 8, 2026

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副本数的变化如何塑造大脑发育障碍:解开突触题

Tianqi Wang1,2, Kubra Trabzonlu1,2, Emily Fullard Jones1,2

  • 1Neuroscience and Mental Health Innovation Institute, Hadyn Ellis Building, Cardiff University, Cardiff, UK.

Psychiatry and clinical neurosciences
|December 23, 2025
PubMed
概括

副本数变异 (CNV) 是与神经发育障碍 (NDD) 相关的遗传变化,如自闭症和ADHD. 这篇评论探讨了CNV如何破坏大脑突触,为新的NDD疗法铺平了道路.

关键词:
副本编号变化 (CNVs) 的变化疾病模型 疾病模型发现药物的发现.神经元发育障碍 (NDD) 是一种神经元发育障碍.突触发展突触的发展.

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