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Updated: Jan 8, 2026

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新的皮里米丁-提亚类混合物的抗糖尿病评价得到了酶动力学研究和计算分析的认可

Gobind Kumar1, Pule Seboletswe1, Neha Manhas1

  • 1School of Chemistry and Physics, University of KwaZulu Natal, Westville, Durban, South Africa.

Chemical biology & drug design
|December 23, 2025
PubMed
概括

新的pyrimidine-thiazole混合物在抑制碳水化合物解酶方面表现有前途,为治疗糖尿病提供了潜在的新策略. 与acarbose相比,8j化合物对α-葡萄糖酶和α-氨基酶表现出更高的抑制活性.

关键词:
ADME/TT 在这里.DFT计算的计算方法它具有抗糖尿病活性.分子对接的分子对接.α-氨酸酶的使用α-葡萄糖酸酶的使用.

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