使用数字心理健康应用程序的成年人坚持和保留的动态指标:来自Brighten研究的纵向观察分析
Dylan Hamitouche1,2, Youcef Barkat2,3, Deven Parekh2
1Department of Medicine, McGill University, Montreal, QC, Canada.
JMIR human factors
|December 23, 2025
概括
参与者的抑郁轨迹和感知到的改善显著影响数字健康研究中的坚持和保留. 了解这些因素可以提高数据收集和试验通用性.
科学领域:
- 数字健康数字健康
- 临床试验中的临床试验.
- 生物标志物验证的验证方法
背景情况:
- 移动卫生技术需要验证的数字生物标志物.
- 远程数字健康研究遭受高消耗和低坚持,潜在的偏见结果.
- 参与者遵守和保留对于可靠的数字生物标志物验证至关重要.
研究的目的:
- 在数字健康研究中确定参与者保留和遵守的纵向指标.
- 制定改善远程试验数据收集的策略.
- 了解参与者退出和不坚持如何塑造研究队列.
主要方法:
- 布莱顿研究的二次分析 (2个基于智能手机的远程RCT).
- 招募了2193名参与者,评估了用于抑郁症治疗的移动应用程序.
- 根据定期填写数字问卷,分析静态和动态措施来评估附加,参与和保留.
主要成果:
- 在2201名参与者中,有1093人完成了至少一个非基线问卷 (完成率中位数为37.6%).
- 较低平均抑郁症和感知临床改善的参与者观察到更高的坚持.
- 在坚持和参与方面发现了显著的人口差异;基线抑郁预测了戒断,而症状改善与更好的坚持和保留有关.
结论:
- 参与者的临床轨迹和感知到的改善是参与,坚持和保留的关键指标.
- 纵向指标可以改善数字健康研究结果的解释.
- 了解这些指标可以为策略提供信息,以促进未来试验中的保留和坚持.
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