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Open Angle Glaucoma: Treatment01:27

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
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[对形中度测量方法的比较评估]

S E Avetisov1,2, V V Averich1,3, A V Volzhanin1

  • 1Krasnov Research Institute of Eye Diseases, Moscow, Russia.

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概括

角膜 (KC) 改变角膜生物力学,影响眼内压力 (IOP) 的测量. 不同的测音仪显示出差异性,较低的读数表明KC患者的角膜健康和厚度较差.

关键词:
角膜生物机械参数 角膜生物机械参数眼内压力 眼内压力形 (keratoconus) 是一种形.度学度学是指测量度的方法.测压仪的读数

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科学领域:

  • 眼科医生 眼科 眼科
  • 生物医学工程 生物医学工程
  • 角质科学 角质科学

背景情况:

  • 角膜 (KC) 呈现慢性角膜变化,使眼内压力 (IOP) 测量解释复杂化.
  • 角膜的生物力学特性和厚度显著影响度计读数.
  • 考虑到角膜变异性,分析度数据是一种有前途的方法,用于在KC中准确评估IOP.

研究的目的:

  • 为了比较评估度测量读数从各种设备在角膜患者.
  • 评估角膜生物力学特征和厚度对KC中的IOP测量的影响.
  • 为了确定不同测色仪方法在改变角膜特性的情况下的表现.

主要方法:

  • 分析了167名双边KC患者 (334只眼睛).
  • 根据角膜歇斯底里 (CH),角膜抵抗因子 (CRF) 和中央角膜厚度 (CCT) 使用眼响应分析仪 (ORA) 和Corvis ST.形成子组.
  • 使用肺动力计,ORA,反弹计 (RT),动态轮计 (DCT) 和马克拉科夫计来测量内压.

主要成果:

  • 在子组之间观察到度计读数的统计学上显著差异 (p<0.05).
  • 肺动力计和ORA (IOPg) 显示出最高的变化率 (39-50%),较低的IOP与较差的生物力学和较薄的角膜相关联.
  • 其他方法 (ORA IOPcc,RT,DCT,Maklakov) 的可变性较小 (≤26%).

结论:

  • 在KC中角膜生物力学的变化导致IOP值的低估,无论测量方法如何.
  • 角膜的特性显著影响了在角质中IOP评估的准确性.
  • 进一步研究KC中的设备特定性能是有必要的.