国家毒物数据系统®:使用语言模型对出版趋势和主题建模的文献综述
Bernard Weigel1,2, Quincy McCrary3, Kara Zweerink2,4
1Department of Emergency Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Clinical toxicology (Philadelphia, Pa.)
|December 23, 2025
概括
使用国家毒物数据系统 (National Poison Data System®) 的研究显示了显著的增加,重点关注儿科和阿片类药物中毒. 这突出了系统的亮点.
科学领域:
- 毒理学 毒理学 毒理学
- 公共卫生 公共卫生
- 生物医学研究生物医学研究
背景情况:
- 国家毒素数据系统是毒理学研究和公共卫生监测的重要资源.
- 在同行评审文献中使用国家毒药数据系统®数据进行的研究缺乏全面的分析.
- 本研究通过评估出版趋势和研究主题来解决这一差距.
研究的目的:
- 用国家毒物数据系统®数据评估出版物中的文献学趋势.
- 在这些出版物中确定主要的研究主题.
- 描述基于国家毒素数据系统®数据传播研究的期刊.
主要方法:
- 在PubMed,Embase和Scopus搜索引用国家毒素数据系统® (2003-2025) 的文章.
- 按期刊主题分类文章,按年份汇总出版物.
- 采用文本嵌入,缩小维度和聚类来识别和标记前10个研究主题.
主要成果:
- 344篇文章符合纳入标准,出版物从2007年稳步增加到2023年的峰值.
- 确定的主要研究主题包括儿科中毒 (187篇文章),阿片类药物中毒 (51),药物错误 (38) 和青少年自我伤害 (34).
- 主要期刊包括临床毒理学 (122篇文章),儿科 (19篇) 和医学毒理学期刊 (16篇),研究涵盖医学毒理学,儿科,药理学,急诊医学和公共卫生.
结论:
- 国家毒素数据系统®数据越来越多地被用于研究,特别是在儿科和与阿片类药物有关的中毒中.
- 发表这项研究的各种期刊强调了它的多学科重要性.
- 加强国家毒素数据系统®的基础设施和可访问性可以促进进一步的研究和扩大调查员的参与.
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