在患有后COVID-19综合征的成年人中,疲劳,认知功能障碍,活动和角色功能以及心理健康如何相互关联? 一个结构方程模型分析分析
Henry Ukachukwu Michael1,2, Fernando Gonzales Aste3, Marie-Josée Brouillette4,3,5
1Division of Clinical and Translational Research, McGill University, Montreal, QC, Canada. henry.michael@mail.mcgill.ca.
概括
后COVID-19综合征 (PCS) 通过疲劳和认知问题显著影响心理健康. 早期解决这些症状可以改善PCS患者的功能和幸福感.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 后COVID-19综合征 (PCS) 带来了持续的挑战,包括疲劳和认知缺陷.
- 这些症状会严重损害日常功能,并对心理健康产生负面影响.
研究的目的:
- 研究PCS患者疲劳,认知功能,日常运作和心理健康之间的复杂关系.
- 了解这些因素是如何相互关联的,并有助于PCS的整体健康负担.
主要方法:
- 分析了来自北克行动后COVID (QAPC) 队列中的535名成年人的横截面数据.
- 结构方程建模 (SEM) 用于评估疲劳,自我报告的认知问题,认知表现,活动/角色功能和心理健康之间的关联.
- 模型根据人口和临床共变量进行了调整.
主要成果:
- 疲劳直接和间接地与较差的心理健康有关,通过自我报告的认知问题有显著的间接影响.
- 疲劳与减少活动和角色功能密切相关.
- 自我报告的认知问题独立预测了较差的心理健康,而客观认知表现显示了与功能但不是心理健康的积极关联.
- 年龄较大,白人种族和疫苗接种情况与更好的结果有关.
结论:
- 疲劳和自我报告的认知困难是PCS精神健康症状的关键因素.
- 这些发现强调了基于症状集群的查对有针对性的认知,心理和功能支持的重要性.
- 建议进行进一步的纵向研究,以确定这些变量之间的时间关系.
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