基线抗胆固醇药物负担在患有过度活性膀的患者中
Morgan Cheeks1, David Lee2, Selma Su2
1Department of Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. Morgancheeks2020@gmail.com.
许多患有过度活动膀 (OAB) 的女性具有高抗胆固醇认知负担 (ACB) 评分,增加风险. 更安全的替代品和解决成本障碍对于改善OAB管理至关重要.
科学领域:
- 泌尿和妇科 泌尿和妇科
- 老年医学 老年医学
- 药理学 药理学是指药理学的学科.
背景情况:
- 过度活跃的膀 (OAB) 影响了许多女性,通常用药物进行管理.
- 抗胆固醇药物带有认知负担 (ACB) 的风险,特别是在老年人中.
- 在OAB患者中量化ACB得分对于安全有效的治疗至关重要.
研究的目的:
- 为了确定基线抗胆固醇性认知负担 (ACB) 在患有过度活性膀 (OAB) 症状的女性中的得分.
- 为了确定与ACB分数升高相关的患者特征.
- 评估ACB分数与OAB治疗选择之间的关联.
主要方法:
- 在一个学术性泌尿内科实践中对242名新出现OAB症状的女性患者进行了回顾性分析.
- 从电子健康记录中抽象基线特征和药物.
- 评估ACB得分使用验证的规模和审查后续的OAB治疗.
主要成果:
- 中位数ACB得分为1;37%的患者具有高风险得分 (≥3).
- 抗胆固醇药物被处方给了3%的患者,71%的高风险ACB患者.
- 高风险的ACB得分与并发症相关,并增加了神经神经调节的可能性.
- 15%的患者被处方为β-3激动剂,但43%的人将成本列为障碍.
结论:
- 有很大比例的OAB女性具有高风险的ACB分数.
- 由于抗胆固醇药的认知风险,需要仔细评估.
- 推广更安全的替代品,如β-3激动剂,并解决成本障碍,可以优化OAB护理.
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