普罗米斯的测量特性 测量与慢性皮肤疾病相关的措施
Michael R Nock1,2, Sherry Ershadi1, Abizairie Sánchez-Feliciano1
1Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
JAMA dermatology
|December 23, 2025
概括
患者报告结果测量信息系统 (PROMIS) 的措施有效评估慢性皮肤病的身体,情绪和社会影响. 这些PROMIS工具证明了有效性,并追踪了阿托皮性皮肤炎,和牛皮等疾病患者的治疗改善.
科学领域:
- 皮肤病学 皮肤病学
- 心理测量 心理测量 心理测量
- 健康 结果 研究 研究 结果
背景情况:
- 患者报告结果测量信息系统 (PROMIS) 为临床整合提供了一般化的患者报告结果测量 (PROMs).
- 在慢性皮肤疾病中PROMIS PROMs的测量特性需要验证.
研究的目的:
- 评估PROMIS短形式测量焦虑,抑郁,社会满意度和社会隔离的有效性,内部一致性和响应能力.
- 评估慢性皮肤病患者单项疼痛和强度测量的构造有效性和响应性.
主要方法:
- 一项美国的在线队列研究招募了自我报告慢性皮肤疾病 (皮炎,,牛皮) 的成年人.
- 参与者完成了基线和3个月的随访调查,包括PROMIS措施,皮肤病生命质量指数和Skindex-29.
- 分析了PROMIS措施的结构有效性,内部一致性,构造有效性和响应性.
主要成果:
- PROMIS对焦虑,抑郁,社会满意度和社会隔离的简短措施显示出足够的结构有效性和内部一致性.
- 所有的PROMIS测量都通过已知组和融合有效性测试证明了足够的构造有效性.
- PROMIS的疼痛和强度测量结果显示,反应能力与Skindex-29的症状域相当;社会满意度和隔离度与Skindex-29的功能域保持一致. 与Skindex-29情绪域相比,焦虑和抑郁的测量反应率较低.
结论:
- PROMIS的测量方法已被验证,用于评估慢性皮肤疾病的身体,情绪和社会影响.
- 物理和社会影响的PROMIS措施有效地跟踪慢性皮肤病患者的治疗诱导的改善.
- 这些发现支持将PROMIS措施纳入皮肤病临床实践,以进行全面的患者评估.
更多相关视频
06:31Precision Implementation of Minimal Erythema Dose MED Testing to Assess Individual Variation in Human Inflammatory Response
Published on: October 3, 2019
9.1K
11:07Visualizing and Quantifying Pharmaceutical Compounds within Skin using Coherent Raman Scattering Imaging
Published on: November 24, 2021
3.2K
相关概念视频
01:14Changes in Skin Color: Clinical Perspectives
3.2K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
3.2K
01:23Skin Diseases and Disorders
5.1K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.1K
01:20Measurement of Bioavailability: Pharmacodynamic Methods
206
Pharmacodynamic methods provide insights into a drug's effects on physiological processes over time and play a crucial role in understanding bioavailability and therapeutic efficacy. These methods can be broadly classified into acute pharmacological and therapeutic response approaches, each with distinct mechanisms and applications.The acute pharmacological response method directly correlates a drug's physiological effects, such as ECG or pupil diameter changes, to its time course in the body.
206