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相关概念视频

Dementia01:30

Dementia

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Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
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Alzheimer's Disease: Treatment01:22

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Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
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Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
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Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
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相关实验视频

Updated: Jan 8, 2026

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills
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技术与痴呆症 会议前会议

Ollie Fegter1,2, Angela C Roberts3, Matthew Bona2

  • 1Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
PubMed
概括

对于PPA患者来说,Web应用程序非常可行,使用率很高,技术问题最小. 这项技术支持PPA患者的重要语音语言家庭实践和教育.

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科学领域:

  • 神经学 神经学
  • 语音和语言病理学 语言病理学
  • 人与计算机的交互

背景情况:

  • 初级渐进性失言症 (PPA) 是一种导致语言逐渐衰退的痴呆症,由于干预和临床医生短缺,限制了获得护理的机会.
  • 技术支持的干预措施有望改善PPA患者获得护理的机会.
  • 对于影响PPA群体在Web应用程序使用的因素,还没有进行系统的探索.

研究的目的:

  • 评估基于应用程序的干预对PPA患者的使用和可行性.
  • 收集定量参与数据和对用户体验的定性见解.
  • 评估技术在支持PPA干预中的作用.

主要方法:

  • 一个为期12个月的随机对照试验 (通讯桥-2) 涉及95名PPA参与者.
  • 鼓励参与者每周五天完成30分钟的基于应用程序的家庭练习练习.
  • 使用数据 (登录,完成的练习) 和半结构化的研究后访谈 (n=79) 通过描述性统计和主题编码进行了分析.

主要成果:

  • 参与者平均每周登录5.88次,并在每周3.99天完成练习.
  • 大多数用户 (85%) 报告技术问题很少,常见的问题是软件更新或连接.
  • 大多数 (90%) 的人认为基于计算机的格式有帮助,许多 (29%) 的人将应用程序描述为培训后的用户友好,培养信心和动机.

结论:

  • 网络应用程序在支持PPA中的通信和语言干预方面具有很高的使用率和可行性.
  • 所有参与者每周都会使用该应用程序,完成家庭实践练习.
  • 研究结果支持Web应用程序作为PPA家庭实践和教育的可行工具,挑战了对认知沟通障碍的老年人技术使用的假设.