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Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
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阿尔茨海默氏症成像联盟

Cyrus A Raji1, Somayeh Meysami2,3, Soojin Lee4

  • 1Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA.

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概括
此摘要是机器生成的。

保持肌肉质量和减少内脏脂肪与更健康的大脑衰老有关. 较高的肌肉体积与较年轻的大脑年龄相关,而较高的内脏脂肪与较老的大脑年龄相关.

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科学领域:

  • 神经成像是一种神经成像.
  • 老年学是一门学科.
  • 身体组成分析 身体成分分析

背景情况:

  • 从结构性MRI中估计大脑年龄,可以了解阿尔茨海默病的风险因素.
  • 标志着肌肉损失的萨尔科佩尼亚是认知能力下降的潜在危险因素.
  • 研究身体组成和大脑衰老之间的关系对于理解神经退行过程至关重要.

研究的目的:

  • 为了检查身体MRI测量肌肉质量和内脏脂肪与大脑年龄之间的关联.
  • 为了确定肌肉与脂肪的比率是否影响大脑衰老标志物.
  • 探索健康大脑衰老的潜在可修改因素.

主要方法:

  • 1,164名健康参与者接受了全身MRI,以量化肌肉质量和脂肪组织.
  • 大脑年龄是使用3D简单完全卷积网络训练T1加权MRI扫描计算的.
  • 根据性别调整的部分相关性被用来分析身体组成指标和时间/大脑年龄之间的关系.

主要成果:

  • 较高的总正常化肌肉体积 (TNMV) 与较低的时间年龄和大脑年龄有关.
  • 内脏脂肪组织 (VAT) 正常化为肌肉体积与较高的时间和大脑年龄相关.
  • 没有发现大脑年龄差距 (BAG) 和测量的身体组成参数之间存在显著的相关性.

结论:

  • 增加肌肉质量与年轻的大脑年龄有关,这表明有保护作用.
  • 相对于肌肉质量,内脏脂肪的增加与大脑加快衰老有关.
  • 提高肌肉质量和减少内脏脂肪的策略可以促进大脑更健康的衰老,并可能减轻阿尔茨海默氏症的风险.