公共卫生 公共卫生
Phenphichcha Chuchuen1,2, Phot Dhammapeera1, Chavit Tunvirachaisakul2,3,4
1Faculty of Psychology, Chulalongkorn University, Bangkok, Thailand.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
这项研究发现,八次多模式认知刺激计划 (MCSP) 在泰国老年轻度认知障碍 (MCI) 的成年人中显著改善了认知和生活质量. 与对照组相比,干预组表现出更好的认知得分和质量生活.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 轻度认知障碍 (MCI) 是一个重要的全球健康问题,特别是在老年人群中.
- 泰国面临着越来越多的MCI挑战,这增加了老年人痴呆症的风险.
- 多模式认知刺激计划 (MCSP) 提供一种非药物治疗方法来缓解认知衰退.
研究的目的:
- 评估8次MCSP对泰国老年人诊断患有MCI的认知功能和生活质量 (QOL) 的疗效.
- 将MCSP干预结果与随机对照试验设置中的对照组进行比较.
主要方法:
- 一项随机对照试验,涉及66名泰国老年人患有MCI,分为干预 (n=32) 和控制 (n=34) 组.
- 认知评估包括MMSE,CERAD,色迹测试和数字跨度;使用QOL-AD测量QOL.
- 数据分析采用了基平方和t测试用于人口统计,以及用于认知和QOL结果的通用估计方程 (GEE).
主要成果:
- 干预和对照组在人口统计,认知分数或QOL方面没有显著的基线差异.
- 在8次MCSP后,干预组在认知得分和QOL方面比对照组有统计学上的显著改善.
- GEE分析表明,群体,年龄,教育和初始分数显著预测了认知分数的变化,而群体,初始分数和按时间相互作用的群体显著影响了QOL分数.
结论:
- 8次MCSP干预显著提高了泰国老年人患有MCI的认知功能和生活质量.
- 这些发现支持MCSP作为一种有效的非药理策略,用于老年人群中管理MCI.
- 该研究强调了有针对性的认知干预措施对改善MCI患者健康结果的积极影响.
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