公共卫生 公共卫生
Simeng Cui1, Qiumin Qu1, Suhang Shang1
1The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
年龄影响身体质量指数 (BMI) 和认知障碍之间的联系. 较低的BMI (<25 kg/m2) 在老年人 (≥60) 中增加了认知障碍的风险,但BMI在中年人 (40-59) 中没有显著的关联.
科学领域:
- 老年学和认知健康学
- 老龄化的流行病学.
- 公共卫生与营养
背景情况:
- 研究身体质量指数 (BMI) 和认知障碍之间的关系对于了解老龄化人口至关重要.
- 以前的研究还没有完全阐明农村社区中这种关联的年龄依赖细微差别.
研究的目的:
- 检查身体质量指数 (BMI) 和认知障碍之间的年龄相关关系.
- 在40岁及以上的农村人口中分析这一关联.
主要方法:
- 研究了来自两个农村村的1792名40岁以上的人群.
- 收集的数据包括人口统计,生活方式,病史和物理/生化检查.
- 认知功能使用迷你精神状态检查 (MMSE) 进行评估;分析涉及后勤回归,受限制的立方线和按年龄组分层分析 (40-59 vs. ≥60).
主要成果:
- 在230名受试者 (12.8%) 诊断出认知障碍.
- 总的来说,观察到BMI和认知障碍之间存在显著的非线性相关性 (P整体=0.023).
- 在60岁以上的个体中,较低的BMI (<25 kg/m2) 与认知障碍的概率增加有关 (P总=0.038),而在40-59岁的年龄组中没有发现显著的关联 (P总=0.722).
结论:
- 年龄显著改变了BMI和认知障碍之间的关系.
- 在老年人中,更高的BMI (≥25 kg/m2) 对认知衰退的保护作用被建议,而在中年人中,BMI并不是认知功能的重要因素.
- 这些发现凸显了与BMI相关的认知健康策略中年龄特定考虑的重要性.
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