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相关概念视频

Primary Healthcare Services01:30

Primary Healthcare Services

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Primary care promotes wellness and prevents disease. This care includes health promotion, education, protection (such as immunizations), early disease screening, and environmental considerations. Settings providing this type of healthcare include physician offices, public health clinics, school nursing, and community health nursing.
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
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Levels of Health Promotion and Illness Prevention01:26

Levels of Health Promotion and Illness Prevention

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Health promotion allows a person to control the determinants of health, resulting in an improved health status. It enhances the quality of life and reduces premature deaths. Health promotion and illness prevention programs help people make beneficial choices to reduce the risk of disease and disabilities. There are three health promotion and illness prevention levels: primary, secondary, and tertiary prevention.
In primary prevention, actions taken before disease onset prevent the disease from...
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Preventive Healthcare Services01:30

Preventive Healthcare Services

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Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
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Principles of Disease Surveillance01:26

Principles of Disease Surveillance

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Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
439
Healthcare Agencies II01:17

Healthcare Agencies II

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There are various healthcare agencies in the United States—some of which are managed by religious institutions and others by different government branches.
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources,...
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Methods Of Healthcare Delivery System01:26

Methods Of Healthcare Delivery System

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At the different levels of the healthcare system, we see varying methods of healthcare used. These methods include managed care systems, case management, and primary healthcare.
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...
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Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
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公共卫生 公共卫生

Kelley M Faber1, Cory Weinfeld2, Abigail Erickson3

  • 1National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD), Indianapolis, IN, USA.

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概括
此摘要是机器生成的。

美国国家老年阿尔茨海默氏病家庭研究研究所 (NIA-AD FBS) 是全球最大的家族阿尔茨海默氏病数据库,为遗传研究提供了宝贵的数据和生物样本. 140多个出版物已经利用了这个资源,促进了对阿尔茨海默氏症遗传学的理解.

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科学领域:

  • 遗传学 遗传学 是一个
  • 神经科学是一个神经科学.
  • 生物医学研究生物医学研究

背景情况:

  • 国家老年阿尔茨海默氏病家庭研究研究所 (NIA-AD FBS) 成立于2002年,是一项多站点的纵向倡议.
  • 它的主要目标是为全球调查人员提供全面的数据和生物样本资源.
  • 该研究旨在促进阿尔茨海默病领域的研究人员之间的合作和资源共享.

研究的目的:

  • 招募阿尔茨海默病 (AD) 患病率高的家庭,包括晚发病 (LOAD) 和早期发病 (EOAD) 的家庭.
  • 为了研究目的,从参与者那里收集大量的临床,遗传和生物数据.
  • 促进基因研究,调查家族性阿尔茨海默病的潜在原因.

主要方法:

  • 招募至少有两个受影响个体和一个愿意的一级亲属的家庭.
  • 收集各种生物样本,包括DNA,血和PBMC,以及临床和认知数据.
  • 在多个地点进行统一的评估,有面对面或远程评估和移动瘤手术服务的选择.

主要成果:

  • 招募了1756个家庭,包括来自高加索,非洲裔美国人和西班牙裔族群的9682名家庭成员.
  • 汇集了丰富的数据集,包括纵向临床数据,认知评估,家族史和各种生物样本.
  • 生成的基因型数据包括APOE,GWAS,WES,WGS,大脑甲基化,RNA测序和生物标记数据.

结论:

  • NIA-AD FBS代表了世界上最大的家族阿尔茨海默病研究队列.
  • 这项研究的数据和样本在140多篇关于阿尔茨海默氏症遗传学的出版物中发挥了重要作用.
  • 由NIA-AD FBS提供的全面资源对于促进对阿尔茨海默病的科学理解至关重要.