公共卫生 公共卫生
Carmen M Colceriu1,2, Alex López1,2, Pablo Aguilar1,2,3
1Global Health Institute Barcelona (ISGlobal), Barcelona, Spain.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
社区可行性与老年人和痴呆症患者的注意力更好有关. 更高的可行性也保护了认知能力不受损的个人的大脑结构,随着年龄的增长.
科学领域:
- 神经科学是一个神经科学.
- 老年学是指老年学的学科.
- 城市规划 城市规划
背景情况:
- 身体活动支持认知功能和老化中的大脑健康.
- 邻里可行性,一个衡量行人友好性的标准,可能会促进身体活动.
- 在老年人中,研究了可行性,执行功能和大脑结构之间的关联.
研究的目的:
- 评估邻里可行性与执行功能和灰色物质 (GM) 量的关联.
- 调查认知能力正常 (CU) 个体和轻度认知障碍 (MCI) 或痴呆症患者的可行性和年龄之间的相互作用.
主要方法:
- 包括来自UBRAIN研究的1543名参与者 (CU,MCI,痴呆症).
- 评估了执行功能和基于MRI的GM体积.
- 用8个因子的指数测量了可行性,该指数是在住宅100米半径内的8个因素.
主要成果:
- 在整个样本中,更高的可行性与更好的注意力相关 (WAIS Digits前进分数).
- 这种关联在CU和痴呆症组中是显著的,但不是MCI.
- 在CU个体中,增加的可行性减轻了与年龄相关的转基因基因体积的缓慢-平行性下降.
结论:
- 居住在可步行的社区与CU个体和痴呆症患者的注意力更好有关.
- 步行能力可能会作为对认知衰老和痴呆症的保护因素.
- 需要进一步的研究来确认体力活动是否会介导这种保护作用.
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