公共卫生 公共卫生
1SensifyLife, Middleton, WI, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
一个新的数字系统,ScentAware,评估与阿尔茨海默病 (AD) 相关的嗅觉缺陷. 该系统使用移动应用程序和云平台,以便在不同人群中更容易收集和分析数据.
科学领域:
- 神经科学是一个神经科学.
- 数字健康数字健康
背景情况:
- 嗅觉缺陷与阿尔茨海默病 (AD) 病理学和tau进展密切相关.
- 传统的纸笔嗅觉测试对纵向研究和自我评估提出了挑战.
- 数字平台为认知评估提供了增强的工作流程,数据捕获和用户可访问性.
研究的目的:
- 开发和验证ScentAware,一个用于嗅觉评估的数字系统.
- 评估ScentAware在不同国际群体中的可行性和文化适应性.
- 探索数字嗅觉测试在神经退行性疾病研究中的实用性.
主要方法:
- ScentAware包括一个含有嗅觉刺激剂的测试套件,一个通过QR码识别气味的移动应用程序 (SensifyAware),以及一个用于数据管理的云平台.
- 该系统使用强制选择问卷,其中包含文化适应的气味选项和当地语言 (斯瓦希里语,阿拉伯语).
- 在三个不同的队列 (肯尼亚,埃及,印度) 中正在进行验证,印度使用了缩写版本.
主要成果:
- 该ScentAware平台展示了高用户参与度和接受度,在认知正常群体中完成率高.
- 数字嗅觉测试显示可接受的内部一致性 (克朗巴赫的α = 0.711).
- 从正在进行的研究中进行的中期分析将被介绍.
结论:
- 在神经退行性疾病研究中,ScentAware为嗅觉评估提供了一个有前途的数字解决方案.
- 该系统的设计促进了文化适应,可访问和高效的数据收集在不同的人口.
- 进一步的验证和分析将阐明ScentAware在了解阿尔茨海默病和相关认知变化方面的作用.
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