公共卫生 公共卫生
Meng Wei1, Qiumin Qu2, Suhang Shang2
1First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
这项研究发现,在农村成年人中,冠状动脉心脏病 (CHD) 和认知障碍之间没有直接联系. 然而,心血管疾病和糖尿病的结合显著增加了认知障碍的风险.
科学领域:
- 老年学是指老年学的学科.
- 心脏病学 心脏病学
- 神经学 神经学
背景情况:
- 心血管疾病 (CVD) 和认知障碍是主要的公共卫生问题.
- 像高血压和肥胖等共同的风险因素将心血管疾病和认知能力下降联系起来.
- 以前对心血管疾病和认知障碍的研究主要涉及住院患者.
研究的目的:
- 调查冠心病 (CHD) 和认知障碍之间的相关性.
- 专注于40岁及以上的农村人口.
- 检查伴随性疾病对心脏病患者认知功能的影响.
主要方法:
- 对1833名40岁以上的农村居民进行了横截面研究.
- 使用迷你精神状态检查 (MMSE) 评估认知功能.
- 多变量逻辑回归调整以考虑混因素.
主要成果:
- 未经调整的分析显示,CHD患者的认知障碍较高 (24.6%对12.9%).
- 调整后的分析显示,心血管疾病和认知障碍之间没有统计学上显著的关联 (OR=1.265).
- 结合糖尿病的CHD显著增加了认知障碍的风险 (OR=4.712).
结论:
- 在冠状动脉心脏病和认知障碍之间没有发现直接关联.
- 心血管疾病和糖尿病的结合显著增加了认知障碍的风险.
- 建议进行进一步的前性研究,采用更大的样本大小.
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