公共卫生 公共卫生
Kevin A Gonzalez1, Rachel Membreno2, Wassim Tarraf3
1University of California, San Diego, La Jolla, CA, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
睡眠障碍和白天嗜睡与西班牙裔/拉丁裔成年人主观认知衰退 (SCD) 的增加有关. 这些睡眠表型可能有助于识别有认知问题的风险的个体.
科学领域:
- 睡眠科学 睡眠科学
- 认知神经学 认知神经学
- 公共卫生 公共卫生
背景情况:
- 睡眠问题与认知能力下降有关,这是痴呆症的前体.
- 基于表型的方法越来越多地用于睡眠研究,因为症状异质性.
- 在不同人群中,睡眠表型与主观认知衰退 (SCD) 之间的关系需要进一步研究.
研究的目的:
- 在一大批西班牙裔/拉丁裔个体中,检查睡眠表型与主观认知衰退 (SCD) 之间的关联.
- 在这个人口群体中,确定与认知健康相关的特定睡眠模式.
主要方法:
- 利用了来自西班牙裔社区健康研究/拉丁裔研究 (HCHS/SOL) 和其辅助研究SOL-INCA的数据.
- 采用了15个睡眠变量和4个心血管措施的潜在类别分析来定义睡眠表型.
- 使用日常认知 (ECog-12) 尺度评估SCD,并通过调查加权线性回归分析了与睡眠表型的关联.
主要成果:
- 一个三类解决方案确定了不同的睡眠表型:睡眠障碍,白天嗜睡和最小症状.
- 与最小症状组 (N=2,722) 相比,睡眠障碍 (N=1,886) 和白天嗜睡 (N=943) 组中的个人在所有认知领域报告了显著更多的SCD.
- 在对共变量进行调整后,这些关联仍然存在.
结论:
- 睡眠障碍和白天嗜睡表型都与主观认知衰退 (SCD) 的增加显著相关.
- 睡眠表型方法可能为认知健康提供有价值的见解,特别是在西班牙裔/拉丁裔人口中.
- 研究结果强调了解决睡眠障碍对于维持认知功能的重要性.
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