Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

1.6K
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
1.6K
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

251
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
251
Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

212
Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
212
Brain Imaging01:14

Brain Imaging

629
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
629
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

460
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
460
Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

758
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
758

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Cognitive Trajectories and Subsequent Accelerometer-Measured Movement Behavior in Older Adults.

JAMA network open·2026
Same author

Digital Sleep-Wake Cycle Metrics and Dementia Prediction in Older Adults.

JAMA neurology·2026
Same author

Implications of Cranial Arterial Stenosis and Dolichoectasia for Cerebral Small-Vessel Disease Etiopathogenesis: Findings From a Prospective Mild Stroke Cohort.

Circulation·2026
Same author

Midlife sleep characteristics and Alzheimer's disease biomarkers 20 years later.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Development of a Prognostic Model for Poststroke Dementia Using Multiple International Cohorts: A STROKOG Collaboration Study.

Neurology·2026
Same author

Biomarkers.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026

相关实验视频

Updated: Jan 8, 2026

Hybrid PET/MRI Imaging of Alzheimer's Disease Based on 18F-AV-1451
05:17

Hybrid PET/MRI Imaging of Alzheimer's Disease Based on 18F-AV-1451

Published on: April 18, 2025

751

阿尔茨海默氏症成像联盟

Dillys Xiaodi Liu1, Meredith N Braskie2, Clémence Cavaillès1

  • 1Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, CA, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
PubMed
概括
此摘要是机器生成的。

老年人的睡眠模式和低氧水平与阿尔茨海默氏症 (AD) 中出现的大脑变化有关. 这些发现强调了睡眠在不同人群中对大脑健康的作用.

更多相关视频

Visualization of Amyloid β Deposits in the Human Brain with Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry
09:31

Visualization of Amyloid β Deposits in the Human Brain with Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry

Published on: March 7, 2019

11.0K
Lesion Explorer: A Video-guided, Standardized Protocol for Accurate and Reliable MRI-derived Volumetrics in Alzheimer's Disease and Normal Elderly
12:50

Lesion Explorer: A Video-guided, Standardized Protocol for Accurate and Reliable MRI-derived Volumetrics in Alzheimer's Disease and Normal Elderly

Published on: April 14, 2014

40.8K

相关实验视频

Last Updated: Jan 8, 2026

Hybrid PET/MRI Imaging of Alzheimer's Disease Based on 18F-AV-1451
05:17

Hybrid PET/MRI Imaging of Alzheimer's Disease Based on 18F-AV-1451

Published on: April 18, 2025

751
Visualization of Amyloid β Deposits in the Human Brain with Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry
09:31

Visualization of Amyloid β Deposits in the Human Brain with Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry

Published on: March 7, 2019

11.0K
Lesion Explorer: A Video-guided, Standardized Protocol for Accurate and Reliable MRI-derived Volumetrics in Alzheimer's Disease and Normal Elderly
12:50

Lesion Explorer: A Video-guided, Standardized Protocol for Accurate and Reliable MRI-derived Volumetrics in Alzheimer's Disease and Normal Elderly

Published on: April 14, 2014

40.8K

科学领域:

  • 神经学 神经学
  • 睡眠医学 睡眠医学
  • 神经成像是一种神经成像.

背景情况:

  • 越来越多的证据将睡眠障碍和睡眠呼吸暂停与大脑健康的下降联系在一起.
  • 睡眠架构,夜间低氧症和与阿尔茨海默病 (AD) 相关的神经成像模式之间的关系尚不清楚,特别是在多样化的老年人群中.

研究的目的:

  • 为了研究睡眠宏观架构,夜间低氧症和AD相关的MRI生物标志物在多样化的老年人群中的关联.
  • 为了检查睡眠阶段和睡眠期间氧和度如何与AD的脑成像标志物相关.

主要方法:

  • 健康和衰老大脑研究-健康差异 (HABS-HD) -Dormir研究包括842名不同的老年人 (非西班牙裔白人,西班牙裔,黑人).
  • 家庭睡眠呼吸暂停评估和大脑MRI被用于评估睡眠和AD相关的MRI生物标志物.
  • 多变量回归模型分析了睡眠参数 (睡眠阶段,呼吸暂停-低氧指数,氧和) 与AD特征皮质厚度和白质超强度 (WMH) 之间的关联.

主要成果:

  • 增加轻度睡眠百分比和更长的REM睡眠延迟与AD标志区域的皮质较薄有关.
  • 增加深度睡眠的百分比显示与皮质厚度的反向关联.
  • 在REM睡眠期间更高的呼吸暂停-低氧指数和更低的平均氧和 (<94%) 与更大的白质超强度 (WMH) 体积有关.
  • 对于这些关联,没有发现显著的民族种族相互作用.

结论:

  • 睡眠宏观架构 (轻度/深度睡眠百分比,REM延迟) 和夜间低氧症与MRI上的阿尔茨海默氏症相关模式有关.
  • 这些发现强调了睡眠质量和氧化对老年人群大脑健康的重要性.