公共卫生 公共卫生
Neika Sharifian1,2, Yunnuo Zhu1,2, Felicia R Carey1
1Naval Health Research Center, San Diego, CA, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
军事服务,特别是高风险职业或患有PTSD等疾病,与退伍军人中轻度认知障碍 (MCI) 和阿尔茨海默氏症和相关痴呆症 (ADRD) 的增加率有关. 这突显了与认知衰退有关的独特服务相关风险.
科学领域:
- 老年学和神经学:在老年人群中研究认知衰退和痴呆症.
- 军事健康:检查特定于军事服务人员和退伍军人的健康结果.
背景情况:
- 全球人口老龄化和预期寿命的增加正在增加认知障碍和痴呆症的负担.
- 退伍军人面临的一般衰老风险是轻度认知障碍 (MCI) 和阿尔茨海默氏症和相关痴呆症 (ADRD),以及服务特定因素,如TBI,PTSD和职业暴露.
研究的目的:
- 在9/11后的退伍军人中分析MCI和ADRD的发生率和相关性.
- 为了全面分析,利用来自千年队列研究的20多年的纵向数据.
主要方法:
- 来自千年队列研究 (2001-2024) 的146670名9/11后退伍军人的纵向研究.
- 通过电子健康记录的ICD-9/10代码识别的MCI和ADRD病例.
- 年龄和性别调整后的发病率计算在每10万人/年.
主要成果:
- 发病率:MCI (1759例) 发病率为每10万人/年25.82,ADRD发病率为每10万人/年6.86 (661例).
- 阿尔茨海默病和血管痴呆是最常见的痴呆症.
- 较高的MCI/ADRD率与军队服务,高风险爆炸暴露职业,PTSD,抑郁症,听力损失和吸烟有关.
结论:
- 研究结果表明,独特的与军事有关的风险因素有助于认知障碍和痴呆症的发展.
- 结果可以为政策和干预措施提供信息,以减轻与兵役相关的长期认知健康风险.
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