公共卫生 公共卫生
Adrienne R S Lee1,2, Gretchen E Bandoli2, Lauren L Brown3,4
1Center for Health Disparities Research, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
在中年生活在弱势社区与更快的认知衰退和痴呆风险增加有关,特别是在白人/非西班牙裔老年人中. 这突显了社会经济因素对长期大脑健康的影响.
科学领域:
- 老年学是指老年学的学科.
- 公共卫生 公共卫生
- 神经科学是一个神经科学.
背景情况:
- 邻居的社会经济劣势与较差的认知功能有关.
- 之前的研究是横截面的;需要前性数据.
研究的目的:
- 检查中晚年生活社区剥夺和认知轨迹之间的关联.
- 调查老年人社区劣势和痴呆风险之间的联系.
主要方法:
- 使用区域贫困指数 (ADI) 来衡量社区的劣势.
- 从1998年至2020年分析了认知表现 (单词回忆,序列七) 和痴呆症分类.
- 采用了通用线性混合模型和考克斯的比例危险模型,对共变量进行调整.
主要成果:
- 高邻居劣势与较差的基线认知表现和白人/非西班牙裔和黑人成年人的更快下降有关.
- 西班牙裔/拉丁裔成年人对认知轨迹没有显著影响.
- 在居住在弱势社区的白人/非西班牙裔成年人中观察到认知障碍和可能痴呆的可能性增加.
结论:
- 生活中期到晚期的邻居不利影响白人/非西班牙裔和黑人老年人的认知轨迹.
- 贫困社区特别增加了白人/非西班牙裔老年人的痴呆风险.
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