公共卫生 公共卫生
Ella T Lifset1, Manjot Kaur1, Kayla Ponce1
1University of California, San Diego, La Jolla, CA, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
招募阿尔茨海默病研究人员是一项挑战. 社区外展,虽然昂贵,但证明是有效的,强调需要多样化的招聘策略.
科学领域:
- 神经科学和衰老研究研究
- 临床试验招聘策略
- 阿尔茨海默病 (AD) 病理生理学
背景情况:
- 阿尔茨海默病 (AD) 研究招聘面临着影响查和招生的重大障碍.
- 关于各种招聘策略的比较有效性和成本的数据有限.
- 这项研究评估了来自正在进行的老年妇女在AD高风险的纵向研究的初步招聘数据.
研究的目的:
- 为了比较阿尔茨海默病 (AD) 研究的不同招聘策略的成本效益和入学收益率.
- 通过提供有关招聘方法相对表现的数据,为研究规划提供信息.
- 确定招募参与者进行复杂的AD研究的最佳策略,涉及神经成像和生物采样.
主要方法:
- 妇女:炎症和tau研究 (WITS) 联系了540名年龄≥65岁的轻度认知障碍和高AD多原风险的个人.
- 招聘策略包括地理定向邮件,关联团体推 (AG),生成联系人列表 (GCL) 和社区宣传.
- 收集每位参与者成本和招生收益率的数据,并在六个月的时间内对四种策略进行比较.
主要成果:
- 在540名接触者中,有213人完成了查,70人被录取.
- 附属集团推 (AG) 是最具成本效益 (无成本),而社区推广是最昂贵的 (365.92美元/参与者).
- 地理定向邮件 (37.4%) 和社区外展 (36.6%) 获得了最高的平均注册参与者数量.
结论:
- 招募AD研究需要大量的财务投资,每位参与者估计为200-350美元.
- 社区外展,尽管成本较高,但表现出很高的效率,证明了对社区招聘的持续投资的合理性.
- 目前的招聘方法可能会限制多样性;正在实施新的战略,以吸引代表性不足的群体.
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