公共卫生 公共卫生
Liliana Paloma Rojas-Saunero1, Yingyan Wu1, Yixuan Zhou1
1UCLA Fielding School of Public Health, University of California, Los Angeles, CA, USA.
女性面临的终身痴呆风险高于男性,种族和族群之间存在显著差异,特别是南亚和中国人群. 这些差异凸显了在痴呆症风险研究中需要考虑性别/性别和种族/种族的必要性.
科学领域:
- 老年学是一门学科.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 痴呆症风险研究往往忽视了种族/种族差异,特别是在亚裔美国社区.
- 这项研究涉及痴呆风险的性别/性别和种族/种族差异.
研究的目的:
- 为了比较性别/性别特异性终身痴呆症风险,条件是无痴呆症的生存到60岁.
- 聚焦于加利福尼亚的中国,菲律宾,日本,南亚和非拉丁裔白人老年人.
主要方法:
- 利用一项队列研究,将邮寄调查与电子健康记录 (EHR) 联系起来,从2002年到2020年.
- 包括来自特定种族/族群的60岁以上的参与者,没有先前确诊的痴呆症.
- 使用阿伦-约翰森估计器计算因果特异性痴呆症累积发病率,将死亡作为竞争事件计算.
主要成果:
- 分析了159,477名来自不同种族/族群的参与者.
- 妇女 (38%-49%) 的终身痴呆风险高于男性 (28%-35%),因种族而异.
- 在南亚和中国参与者中观察到最大的性别/性别差异;无痴呆症的死亡率在男性中更高.
结论:
- 60岁之前的终身痴呆风险在女性中高于男性,并且在种族/族群之间有很大的差异.
- 不平等可能受到死亡率和社会/结构因素的影响.
- 强调性/性别,种族和种族在痴呆风险中的交叉性.
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