公共卫生 公共卫生
C Elizabeth Shaaban1,2, Ashley V Hill3, Alyssa Smith4
1University of Pittsburgh, Pittsburgh, PA, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
歧视经历与中年女性自我报告的认知功能恶化有关. 主观认知能力下降,特别是在记忆和执行功能方面,与歧视有关,独立于怀孕的高血压疾病.
科学领域:
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
- 心理学 心理学 心理学
背景情况:
- 晚年大脑健康的持续差异存在于性别/性别和种族群体之间.
- 妊娠高血压障碍 (HDP) 是阿尔茨海默病和相关痴呆症 (ADRD) 的公认中年风险因素.
- 歧视是HDP和认知衰退的新兴风险因素.
研究的目的:
- 评估歧视与中年女性认知功能之间的关联.
- 确定该协会是否独立于HDP.
- 探索受歧视影响的特定认知领域.
主要方法:
- 来自临床队列的580名女性完成了日常歧视量表 (EDS),电话蒙特利尔认知评估 (T-MoCA) 和日常认知量表 (ECog).
- 收集的数据包括人口统计,种族和HDP的历史.
- 使用线性回归模型来测试关联,调整共变量.
主要成果:
- 在EDS上报告的更大的歧视与更差的主观认知功能 (ECog分数) 有显著的关联.
- 在EDS和客观认知表现 (T-MoCA分数) 之间没有发现显著的关联.
- 主观认知的所有领域,特别是组织,记忆,注意力分裂和计划,都与歧视有关.
结论:
- 主观认知措施对歧视的影响比客观措施更敏感.
- 歧视与执行和记忆领域的障碍有关.
- 歧视可能会影响日常功能,并增加生命晚期之前认知障碍的风险.
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