公共卫生 公共卫生
Frank J Wolters1, Peter P M Harteloh2, Frank J A van Rooij1
1Erasmus MC - University Medical Center Rotterdam, Rotterdam, Zuid-Holland, Netherlands.
死亡记录在研究中为痴呆症诊断提供了一种简化方法,但准确性各不相同. 死亡证明显示高特异性但敏感性有限,随着ICD-10编码和更长的痴呆持续时间而改善.
科学领域:
- 流行病学 流行病学
- 老年学是一门学科.
- 公共卫生 公共卫生
背景情况:
- 在纵向研究中确定痴呆症诊断是资源密集的.
- 死亡记录可能为痴呆症诊断提供更有效的替代方案.
- 痴呆症死亡原因编码的准确性尚未完全确定.
研究的目的:
- 评估痴呆症死亡证明的诊断准确性.
- 从死亡率数据评估影响痴呆症诊断准确性的因素.
主要方法:
- 利用了6280名参与者在基于人口的鹿特丹研究的数据.
- 对比生活中的痴呆症诊断与1989-2018年的已认证死亡原因 (ICD-9和ICD-10).
- 基于编码,死亡地点,年龄,痴呆症持续时间和并发症的分析一致性.
主要成果:
- 死亡证明证明了痴呆症的高特异性 (>96%).
- 随着时间的推移,敏感性从<10% (ICD-9) 增加到~70% (ICD-10).
- 精度受到ICD版本,死亡年龄,痴呆症持续时间和并发症,特别是中风和心力衰竭的影响.
结论:
- 死亡证明是特定的,但对于痴呆症诊断不是高度敏感的.
- 在老年人,最近被诊断或心血管并发症的人群中,准确性较低.
- 这些发现有助于在纵向痴呆症研究中使用死亡率数据与人体查相比.
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