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相关概念视频

Primary Healthcare Services01:30

Primary Healthcare Services

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Primary care promotes wellness and prevents disease. This care includes health promotion, education, protection (such as immunizations), early disease screening, and environmental considerations. Settings providing this type of healthcare include physician offices, public health clinics, school nursing, and community health nursing.
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
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Levels of Health Promotion and Illness Prevention01:26

Levels of Health Promotion and Illness Prevention

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Health promotion allows a person to control the determinants of health, resulting in an improved health status. It enhances the quality of life and reduces premature deaths. Health promotion and illness prevention programs help people make beneficial choices to reduce the risk of disease and disabilities. There are three health promotion and illness prevention levels: primary, secondary, and tertiary prevention.
In primary prevention, actions taken before disease onset prevent the disease from...
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Preventive Healthcare Services01:30

Preventive Healthcare Services

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Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
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Principles of Disease Surveillance01:26

Principles of Disease Surveillance

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Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
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Healthcare Agencies II01:17

Healthcare Agencies II

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There are various healthcare agencies in the United States—some of which are managed by religious institutions and others by different government branches.
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources,...
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Methods Of Healthcare Delivery System01:26

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At the different levels of the healthcare system, we see varying methods of healthcare used. These methods include managed care systems, case management, and primary healthcare.
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...
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Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
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公共卫生 公共卫生

Prathima Arvind1, Piu A Das2, Sohan Angelo A2

  • 1Centre for Brain Research, Indian Institute of Science, Bangalore, Karnataka, India.

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概括
此摘要是机器生成的。

这项研究发现,一种特定的ACE2基因多态性 (rs2074192) 与女性的COVID-19风险增加有关,但与男性无关. 需要进一步的研究来了解这些性别特异性的遗传影响.

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科学领域:

  • 遗传学 遗传学 是一个
  • 流行病学 流行病学
  • 传染性疾病 传染性疾病

背景情况:

  • 人类ACE2是冠状病毒 (COVID-19) 进入宿主细胞的关键受体.
  • ACE2基因中的遗传变异 (SNP) 影响不同人群的COVID-19易感性.
  • 塔塔长度衰老研究 (TLSA) 队列为调查与衰老相关疾病的遗传关联提供了宝贵的资源.

研究的目的:

  • 在TLSA队伍中调查特定的ACE2基因多态和COVID-19感染风险之间的关联.
  • 探索对COVID-19遗传易感性的潜在性别特异性差异.

主要方法:

  • 利用了TLSA队列中的696名参与者的基线数据.
  • 使用PLINK v1.9.0.0.进行质量控制和表型-基因型分析.
  • 包括480名参与者在最终的基因型-表型分析中,按性别分层并根据年龄进行调整.

主要成果:

  • ACE2多态 rs2074192 (TT+TC基因型) 与女性的COVID-19风险增加显著相关 (OR=1.69,p=0.02).
  • 在两性之间没有发现rs2285666或rs1978124的显著关联.
  • rs2074192的多态性与男性的COVID-19风险没有显著的关联 (OR=1.59,p=0.13).

结论:

  • ACE2基因多态可能对COVID-19易感性产生性别特异性影响.
  • rs2074192的多态表现为女性对COVID-19的潜在遗传倾向.
  • 需要进一步的研究来阐明这些性别特异性遗传发现的生物机制和临床影响.