公共卫生 公共卫生
Lily Francis1,2,3, Alexa S Beiser4,5,6,7, Sophia Lu8
1Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, UT Health San Antonio, San Antonio, TX, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
中度至严重的听力损失会增加痴呆症的风险,特别是在70岁以下的个人和APOE-ε4载体中. 早期查和听力损失的管理可能有助于降低痴呆风险.
科学领域:
- 神经科学是一个神经科学.
- 流行病学 流行病学
- 老年学是一门学科.
背景情况:
- 听力损失是痴呆症的一个已知的风险因素,但具体的痴呆症亚型和修饰因素仍然不清楚.
- 这项研究调查了听力损失和各种类型的痴呆症之间的联系,包括阿尔茨海默病和血管痴呆症.
研究的目的:
- 为了检查听力损失和全因痴呆症,阿尔茨海默病和血管痴呆症之间的联系.
- 为了确定Framingham研究队列中的听力损失-痴呆症关联的潜在效果修饰者.
主要方法:
- 利用了来自弗雷明汉研究的数据,包括60岁以上的参与者,听力测量结果和长达40年的痴呆症监测.
- 听力损失定义为纯色调平均值> 25dB在更好的耳朵,使用NHATS标准分类严重程度.
- 使用已确定的临床标准 (DSM IV,NINCDS-ADRDA,NINDS-AIREN) 诊断出痴呆症亚型 (所有原因,阿尔茨海默氏症,血管).
主要成果:
- 中度至重度听力损失与所有原因痴呆的风险增加30%有关.
- 这种关联在听力评估时70岁以下的个体中更为明显.
- 在APOE-ε4载体中,风险显著增加,特别是在阿尔茨海默病中.
结论:
- 听力损失与所有原因痴呆症,阿尔茨海默病和血管痴呆症的风险增加有关.
- 70岁以下的人和携带APOE-ε4基因变异的人的风险最大.
- 中年查和听力损失的管理可能会减轻痴呆症风险.
更多相关视频
09:33Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India
Published on: December 23, 2022
2.6K
07:20Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
Published on: January 28, 2014
37.1K
相关概念视频
01:30Primary Healthcare Services
1.9K
Primary care promotes wellness and prevents disease. This care includes health promotion, education, protection (such as immunizations), early disease screening, and environmental considerations. Settings providing this type of healthcare include physician offices, public health clinics, school nursing, and community health nursing.
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
1.9K
01:26Levels of Health Promotion and Illness Prevention
14.1K
Health promotion allows a person to control the determinants of health, resulting in an improved health status. It enhances the quality of life and reduces premature deaths. Health promotion and illness prevention programs help people make beneficial choices to reduce the risk of disease and disabilities. There are three health promotion and illness prevention levels: primary, secondary, and tertiary prevention.
In primary prevention, actions taken before disease onset prevent the disease from...
In primary prevention, actions taken before disease onset prevent the disease from...
14.1K
01:30Preventive Healthcare Services
1.8K
Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
1.8K
01:26Principles of Disease Surveillance
439
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
439
01:17Healthcare Agencies II
1000
There are various healthcare agencies in the United States—some of which are managed by religious institutions and others by different government branches.
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources,...
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources,...
1000
01:26Methods Of Healthcare Delivery System
3.9K
At the different levels of the healthcare system, we see varying methods of healthcare used. These methods include managed care systems, case management, and primary healthcare.
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...
3.9K