公共卫生 公共卫生
Claire C Meunier1, Paola Gilsanz2, María M M Corrada3
1University of California, Davis, Davis, CA, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
身体质量指数 (BMI) 显示男性和女性与口头情节性记忆 (VEM) 衰退的不同关联. 中年肥胖与男性的VEM下降速度更快有关,而中年BMI较高与女性的VEM下降速度更慢有关.
科学领域:
- 神经科学是一个神经科学.
- 老年学是指老年学的学科.
- 公共卫生 公共卫生
背景情况:
- 之前的研究表明,身体质量指数 (BMI) 和认知方面的性别/性别差异.
- 在不同的老年人中,BMI与不同性别的认知衰退之间的关联需要进一步调查.
研究的目的:
- 检查中晚年BMI如何影响种族多样化的老年人群的认知衰退 (口头情节性记忆和执行功能).
- 调查这些BMI认知关联中的潜在的性别/性别差异.
主要方法:
- 利用了来自1711个种族/种族多样化的老年人的数据,跨越三个队伍.
- 使用标准化的神经心理测试测量了口头情节性记忆 (VEM) 和执行功能 (EF).
- 分析了中年和晚年BMI,使用种族特定的切断值,并使用线性混合模型来评估认知衰退中的性别/性别差异.
主要成果:
- 在任何性别组中,中年或晚年BMI都与执行功能下降无关.
- 中年BMI (肥胖,超重) 和晚年超重BMI和VEM下降之间的关联因性别而异.
- 在女性中,中年BMI较高与VEM下降速度较慢有关;在男性中,肥胖中年BMI与VEM下降速度较快有关.
结论:
- 中年和晚年BMI在男性和女性中表现出与口头情节性记忆力下降的差异关联.
- 这些发现表明,性别/性别之间的认知衰老背后可能存在不同的生物学机制.
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