公共卫生 公共卫生
Hitesh Pradhan1, Priya Chatterjee1, Jonas S Sundarakumar1
1Centre for Brain Research, Indian Institute of Science, Bangalore, Karnataka, India.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
白质高强度 (WMH) 与海马缩 (HA) 和老年印度人的认知衰退有关. 内WMH显示与HA的关联性最高,强调需要进行脑血管干预.
科学领域:
- 神经成像是一种神经成像.
- 脑血管健康 脑血管健康
- 认知老龄化 认知老龄化
背景情况:
- 白质超强度 (WMH) 表明大脑血管变化,与海马有关.
- 海马缩 (HA) 与认知障碍有关.
- 印度农村人口中WMH和HA之间的特定关系还不清楚.
研究的目的:
- 为了研究白质强度过高 (WMH) 和海马缩 (HA) 之间的特定区域的关联.
- 探索WMH和HA对老龄化印度群体认知功能的影响.
主要方法:
- 分析了来自CBR-SANSCOG研究的1253名参与者 (45岁以上) 的MRI数据.
- 测量了海马缩 (HA) 和区域WMH体积 (周心室,皮层下,皮层下,皮层下,皮层下).
- 一般化的线性模型评估了WMH,HA和认知得分之间的关联,并对共变量进行了调整.
主要成果:
- 较高的HA与较差的注意力和复合认知评分相关.
- 周周结膜,下皮层,下层和上皮层WMH的体积增加都与更高的HA相关.
- 内WMH显示出对HA的贡献相对较高.
结论:
- 特定区域的WMH体积对海马缩 (HA) 有不同的影响.
- 内WMH体积与HA有显著的关联.
- 早期评估WMH和脑血管风险修饰对于保持老年人群的认知功能至关重要.
更多相关视频
09:33Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India
Published on: December 23, 2022
2.6K
07:20Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
Published on: January 28, 2014
37.1K
相关概念视频
Primary Healthcare Services
1.9K
Primary care promotes wellness and prevents disease. This care includes health promotion, education, protection (such as immunizations), early disease screening, and environmental considerations. Settings providing this type of healthcare include physician offices, public health clinics, school nursing, and community health nursing.
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
1.9K
Levels of Health Promotion and Illness Prevention
14.1K
Health promotion allows a person to control the determinants of health, resulting in an improved health status. It enhances the quality of life and reduces premature deaths. Health promotion and illness prevention programs help people make beneficial choices to reduce the risk of disease and disabilities. There are three health promotion and illness prevention levels: primary, secondary, and tertiary prevention.
In primary prevention, actions taken before disease onset prevent the disease from...
In primary prevention, actions taken before disease onset prevent the disease from...
14.1K
Preventive Healthcare Services
1.8K
Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
1.8K
Principles of Disease Surveillance
439
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
439
Healthcare Agencies II
1000
There are various healthcare agencies in the United States—some of which are managed by religious institutions and others by different government branches.
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources,...
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources,...
1000
Methods Of Healthcare Delivery System
3.9K
At the different levels of the healthcare system, we see varying methods of healthcare used. These methods include managed care systems, case management, and primary healthcare.
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...
3.9K
