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Updated: Jan 8, 2026

Mouse Footpad Inoculation Model to Study Viral-Induced Neuroinflammatory Responses
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基础科学和病原发生学

Thomas Westergard1

  • 1GSK, Collegeville, PA, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
PubMed
概括

降低的progranulin (PGRN) 水平与神经退行性疾病有关. 一种抗索尔提林抗体 (GSK5862611) 增加了PGRN水平,在细胞模型中逆转了TDP43 G298S变异效应,表明潜在的ALS疗法.

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