公共卫生 公共卫生
Cynthia Williams1, Adam Golden2, Hariom Yadav3
1University of Central Florida, ORLANDO, FL, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
招募各种人群进行肠道微生物组研究对于理解认知疾病至关重要. 社区参与和移动卫生单位等策略可以改善对家庭和少数群体的包容性.
科学领域:
- 微生物组研究的研究.
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 肠道微生物群在营养代谢,认知和免疫系统中发挥着关键作用.
- 微生物组研究越来越多地将肠道细菌,真菌和病毒与认知疾病联系起来.
- 临床试验往往不包括在家的老年人和少数群体,限制了概括性.
研究的目的:
- 审查以证据为基础的战略,以提高对家庭和少数群体微生物组研究的包容性.
- 讨论涉及这些组的临床试验所需的纳入和排除标准.
主要方法:
- 使用CINAL,PubMed,Medline,PsycINFO和Embase进行的文献综述.
- 分析招聘和留住服务不足人群的战略.
- 讨论包括/排除标准和混因素.
主要成果:
- 确定策略:社区参与,文化适当的援助,移动卫生单位,战略伙伴关系.
- 强调了纳入/排除标准对于优化结果的重要性.
- 承认需要在试验中为弱势群体提供足够的支持.
结论:
- 强调微生物组研究中代表性不足的群体的招聘策略.
- 强调了包含/排除标准对于可靠和可概括的发现的重要性.
- 倡导多元化的参与,以解决健康不平等问题和个性化医疗保健.
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