公共卫生 公共卫生
Larry C Shaver1, Su-Bin Park1, Anne-Marie Robert1
1Public Health Agency of Canada, Ottawa, ON, Canada.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
在COVID-19大流行期间,痴呆症发病率略有增加,但全因死亡率显著上升. 由于这些因素,在大流行期间,痴呆症的患病率下降得更快.
科学领域:
- 公共卫生监督 公共卫生监督
- 流行病学 流行病学
- 老年学是一门学科.
背景情况:
- 加拿大慢性疾病监测系统 (CCDSS) 在全国范围内监测慢性疾病.
- COVID-19 疫情影响了健康行为和数据收集.
- 之前的研究指出,在疫情期间,痴呆病例捕获率降低,死亡率增加.
研究的目的:
- 分析2015年至2023年国家痴呆症监测数据.
- 评估COVID-19大流行对痴呆症发病率,死亡率和患病率的影响.
- 检查被诊断为痴呆症的趋势,包括阿尔茨海默病.
主要方法:
- 利用加拿大慢性病监测系统 (CCDSS) 的数据,将医疗保险注册表与行政健康记录联系起来.
- 计算了痴呆症发病率,全因死亡率和流行率的年平均百分比变化 (AAPC).
- 使用年龄标准化估计,比较流行前 (2015-2020) 和流行期间 (2020-2023年).
主要成果:
- 痴呆症发病率:大流行前每年下降<1%,大流行期间每年增加0.2%.
- 所有原因的死亡率:大流行前每年增加<1%,大流行期间每年增加3%.
- 患病率:大流行前每年下降1%;在大流行期间加速到每年下降1.6%.
结论:
- 疫情期间痴呆症患病率的加速下降与死亡率增加和最初发病率下降有关.
- 与流行病相关的因素显著影响了痴呆症监测趋势.
- 持续监测对于了解流行病对痴呆症数据的长期影响至关重要.
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