公共卫生 公共卫生
Rapas Samalapa1, Aisawan Petchlorlian1,2
1Geriatric Excellence Center, King Chulalongkorn Memorial Hospital, The Thai Red Cross Society, Bangkok, Thailand.
高血压,肥胖和社会隔离是影响老年人认知功能和认知能力下降的关键可改变的危险因素. 解决这些问题可以帮助促进老年人群的认知健康.
科学领域:
- 老年学与公共卫生
- 神经科学和衰老研究研究
背景情况:
- 痴呆症的患病率正在上升,这对公众健康构成了重大挑战.
- 认知功能容易受到各种风险因素的影响,因此需要确定可修改的预防策略.
研究的目的:
- 确定与泰国老年人认知功能和衰退相关的可修改的风险因素.
- 为促进老年人群认知健康提供有针对性的干预信息.
主要方法:
- 一项对8,949名60岁以上没有痴呆症的成年人的队列研究在楚拉龙康国王纪念医院 (2018年10月 - 2024年7月) 进行.
- 用蒙特利尔认知评估 (MoCA) 评分 (连续和分类) 评估认知结果.
- 一个随机森林模型分析了风险因素和认知结果之间的关系,包括与MoCA下降相关的因素在2,655名参与者中,随访数据.
主要成果:
- 较低基线MoCA分数的关键风险因素包括受教育程度较低,肥胖,高血压和社会隔离.
- 高血压,肥胖和低体力活动与随着时间的推移MoCA的下降有关.
- 教育不足,高血压,肥胖和社会隔离与基线认知障碍 (MoCA <25) 有关.
结论:
- 高血压,肥胖和社会隔离是影响基线认知状态和老年泰国成年人的认知衰退的重要可改变的风险因素.
- 较低的教育程度和较低的体力活动也是与认知健康相关的关键因素.
- 针对这些因素的有针对性的干预措施对于提高老龄人口的认知健康至关重要.
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