Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Primary Healthcare Services01:30

Primary Healthcare Services

1.9K
Primary care promotes wellness and prevents disease. This care includes health promotion, education, protection (such as immunizations), early disease screening, and environmental considerations. Settings providing this type of healthcare include physician offices, public health clinics, school nursing, and community health nursing.
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
1.9K
Levels of Health Promotion and Illness Prevention01:26

Levels of Health Promotion and Illness Prevention

14.1K
Health promotion allows a person to control the determinants of health, resulting in an improved health status. It enhances the quality of life and reduces premature deaths. Health promotion and illness prevention programs help people make beneficial choices to reduce the risk of disease and disabilities. There are three health promotion and illness prevention levels: primary, secondary, and tertiary prevention.
In primary prevention, actions taken before disease onset prevent the disease from...
14.1K
Preventive Healthcare Services01:30

Preventive Healthcare Services

1.8K
Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
1.8K
Principles of Disease Surveillance01:26

Principles of Disease Surveillance

439
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
439
Healthcare Agencies II01:17

Healthcare Agencies II

1000
There are various healthcare agencies in the United States—some of which are managed by religious institutions and others by different government branches.
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources,...
1000
Methods Of Healthcare Delivery System01:26

Methods Of Healthcare Delivery System

3.9K
At the different levels of the healthcare system, we see varying methods of healthcare used. These methods include managed care systems, case management, and primary healthcare.
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...
3.9K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Intraindividual cognitive variability predicts amyloid beta, tau PET, and dementia conversion in Down syndrome: a potential marker of cognitive resilience.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Promoting Research Excellence in Down Syndrome: Proceedings of the 5th International Conference of the Trisomy 21 Research Society.

Neuromolecular medicine·2026
Same author

Diabetes, impaired fasting glucose, and cognitive trajectories: a multi-cohort study.

medRxiv : the preprint server for health sciences·2026
Same author

CNS-selective plasma p-tau217 accurately captures Alzheimer's disease pathology and progression.

medRxiv : the preprint server for health sciences·2026
Same author

Olfaction, Cognition, and Early Signs of Neurodegenerative Disease in a Community-Based Sample of Older Adults.

Alzheimer disease and associated disorders·2026
Same author

Evaluation of serum as an alternative matrix to plasma for NULISA‑based proteomic blood biomarker measurements.

Scientific reports·2026
Same journal

Unveiling the procoagulant state in Alzheimer's disease: A novel PET imaging strategy.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Estimated labor market outcomes of people progressing from preclinical to early-stage Alzheimer's disease in the United States.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Amyloid exacerbates tau and alpha-synuclein pathologies, behavioral impairments, and neuroinflammation in a mixed dementia model.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Multimorbidity burden and patterns associated with DeepBrainNet-derived brain-age gap in dementia-free older adults: A community-based study.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Reply to "Shifting the emphasis of brain health literacy from individuals to systems to reduce inequalities".

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Shifting the emphasis of brain health literacy from individuals to systems to reduce inequalities.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
查看所有相关文章

相关实验视频

Updated: Jan 8, 2026

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
10:57

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children

Published on: August 22, 2012

24.2K

公共卫生 公共卫生

Marissa A Gogniat1,2, Lindsey Jorda1, Joseph Storey2

  • 1University of Pittsburgh Alzheimer's Disease Research Center, Pittsburgh, PA, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
PubMed
概括
此摘要是机器生成的。

久坐不动行为会影响老年人的认知功能,尤其是在与阿尔茨海默病生物标志物相互作用时. 较低的静坐时间与那些生物标志物水平较高的人的认知能力更好有关,而较高的静坐时间有利于那些生物标志物水平较低的人.

更多相关视频

Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India
09:33

Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India

Published on: December 23, 2022

2.6K
Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K

相关实验视频

Last Updated: Jan 8, 2026

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
10:57

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children

Published on: August 22, 2012

24.2K
Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India
09:33

Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India

Published on: December 23, 2022

2.6K
Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K

科学领域:

  • 老年学是指老年学的学科.
  • 神经科学是一个神经科学.
  • 认知科学 认知科学

背景情况:

  • 久坐不动的行为在老年人中很常见,并且与不良健康结果有关,包括痴呆风险.
  • 老年人的久坐行为和认知功能之间的关系尚未完全被理解,结果各不相同,神经生物学机制不清楚.
  • 这项研究调查了久坐不动行为和阿尔茨海默病 (AD) 生物标志物之间的相互作用,用于预测非痴呆老年人的认知功能.

研究的目的:

  • 为了检查静坐行为如何与阿尔茨海默病 (AD) 生物标志物 (粉样蛋白-β和) 相互作用,以影响老年人的认知表现.
  • 探索在衰老中静坐行为和认知之间的关联背后的神经生物学机制.
  • 为了确定AD生物标志物水平是否会改变久坐行为和认知结果之间的关系.

主要方法:

  • 来自匹兹堡大学ADRC临床核心的41名老年人的子集与加速计和PET成像数据进行了分析.
  • 使用Fitbit Inspire 3测量了久坐不动的行为,通过神经心理测试测量认知功能,使用PET成像测量了AD生物标志物 (粉样β,tau).
  • 适度模型被用来评估久坐行为和AD生物标志物之间对认知结果的相互作用,并根据人口因素进行调整.

主要成果:

  • 久坐不动的行为与全球粉样蛋白负担有显著的相互作用,影响了字母流性,语言复合和复杂的注意力.
  • 久坐不动的行为也与超时的tau负担相互作用,影响对抗命名.
  • 具体来说,较长的静坐时间与低粉样β和tau负担的个体的更好的认知相关,而较低的静坐时间与高生物标志物负担的个体的更好的认知相关.

结论:

  • 久坐不动的行为和AD生物标志物相互作用,影响老年人的认知表现.
  • 阿尔茨海默病生物标志物负担的水平对于理解久坐行为对认知影响的方向性至关重要.
  • 这些发现强调了修改久坐行为的重要性,特别是在患有阿尔茨海默症生物标志物风险较高的老年人中.