公共卫生 公共卫生
Femke Te Hoonte1,2, Liset M Rietman1, Kirsten E J Wesenhagen1
1National Institute for Public Health and the Environment, Bilthoven, Utrecht, Netherlands.
较高的体重指数 (BMI) 和腰围 (WC) 与成年人的认知功能下降有关. 在55岁及以上的男性中,腹部肥胖加速了认知能力的下降.
科学领域:
- 神经科学是一个神经科学.
- 流行病学 流行病学
- 老年学是指老年学的学科.
背景情况:
- 肥胖是一种已知的痴呆风险因素,与认知能力下降存在复杂的关联.
- 肥胖时间和指标 (BMI,WC) 对认知的影响需要进一步研究.
研究的目的:
- 检查身体质量指数 (BMI),腰围 (WC) 和腹部肥胖与认知功能水平和下降之间的关系.
- 调查这些关联是如何根据年龄和性别不同.
主要方法:
- 利用了3,918名Doetinchem队列研究参与者的数据 (在基线时年龄为45-70岁).
- 随着时间的推移,评估了BMI,WC和认知领域 (全球认知,记忆,灵活性,处理速度).
- 采用线性混合模型,调整社会人口统计和生活方式因素,以性别和年龄分层.
主要成果:
- 在男性和女性中,高BMI和WC与所有四个认知领域的较低水平相关.
- 在BMI/WC和加速认知衰退之间没有发现显著的关联.
- 腹部肥胖与全球认知和灵活性的加速下降有关,但仅在基线时55岁以上的男性中.
结论:
- 较高的BMI和WC与成人认知功能水平的降低有关.
- 虽然通常与加速衰退无关,但腹部肥胖在老年男性中显示出特定的关联.
- 研究结果强调了体重管理对于维持整个生命周期的认知健康的重要性.
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