公共卫生 公共卫生
Diana Morales1, Jacqueline Guzman2, Yuliana Soto3
1University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
拉丁裔面临高阿尔茨海默氏症.
科学领域:
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
- 老年学是指老年学的学科.
背景情况:
- 美国的拉丁裔人患阿尔茨海默病和相关痴呆症 (ADRD) 的风险较高.
- 可修改的风险因素,如低教育,睡眠不足,不活动,肥胖,不健康的饮食和糖尿病,对ADRD风险有很大影响.
- 这些因素经常同时发生,需要研究它们对认知障碍的综合影响.
研究的目的:
- 研究拉丁裔人口中ADRD风险因素和认知结果之间的关联.
- 识别流行风险因素组合及其与认知功能的相关性.
主要方法:
- 一项涉及中年至老年拉丁裔的横截面研究的二次分析.
- 数据收集包括人口统计,慢性疾病,体力活动,饮食遵守 (MIND饮食) 和认知评估 (MMSE,Trails A/B,口语流).
- 风险因素被二分化,总结以确定集群,并使用Pearson的相关性分析了患病率和与认知措施的相关性.
主要成果:
- 该研究包括61名拉丁裔参与者,平均年龄为58.6岁; 77%是女性,41.7%的收入低.
- 观察到高患病率的危险因素:63.3%的受教育程度低,55.7%的睡眠时间少于7小时,60.7%的慢性疾病,58.8%的肥胖.
- 风险因素的聚类与全球认知 (MMSE分数) 和口语流性负相关,与认知处理速度 (Trails A完成时间) 有正相关.
结论:
- 在拉丁裔中,较多的ADRD风险因素与较差的执行功能和全球认知表现有关.
- 大多数参与者都有多种风险因素,主要是教育程度低,睡眠不足,慢性疾病和肥胖.
- 针对多种可修改的风险因素的有针对性的干预措施对于缓解这一群体认知衰退至关重要.
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