公共卫生 公共卫生
Paola Filigrana1, Linda C Gallo2, Myriam Fornage3,4,5
1Albert Einstein College of Medicine, Bronx, NY, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
在整个生命中保持高社会经济地位与西班牙裔/拉丁裔成年人轻度认知障碍 (MCI) 的风险较低有关. 这一发现对于在这个不断增长的人口中了解阿尔茨海默氏症和相关痴呆症 (ADRD) 是至关重要的.
科学领域:
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
- 社会学 社会学 社会学
背景情况:
- 阿尔茨海默氏症和相关痴呆症 (ADRD) 对美国西班牙裔/拉丁裔成年人构成重大健康负担.
- 终身社会经济劣势可能导致该人口中ADRD负担较高.
研究的目的:
- 检查社会经济地位 (SEP) 与中老年和老年西班牙裔/拉丁裔成年人的轻度认知障碍 (MCI) 之间的关系.
主要方法:
- 分析了来自西班牙裔社区健康研究/拉丁裔研究 (HCHS/SOL) 和SOL-INCA研究 (n=6351,年龄50-86岁) 的数据.
- 终身SEP被分类 (稳定低,上升流动性,下降流动性,稳定高) 基于儿童和成人SEP.
- 使用逆概率权重的后勤回归评估了生命周期SEP和MCI之间的关联,并对共变量和采样设计进行了调整.
主要成果:
- 9.8%的参与者符合MCI的标准.
- 较高的成人SEP与较低的MCI几率相关 (OR=0.78).
- 在一生中稳定高的SEP显著与较低的MCI几率相关 (OR=0.68).
结论:
- 较高和稳定的生命周期SEP与中年和老年西班牙裔/拉丁裔成年人的更好的认知衰老有关.
- 这些发现对于解决该人口群体中预计ADRD病例的增加至关重要.
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