公共卫生 公共卫生
Rebecca Mullen1, Lauren Gunn-Sandell1, Nichole E Carlson1
1University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
孤独在老年人中很普遍,并且与阿尔茨海默病 (AD) 症状严重程度有关. 更高的孤独与无症状有关,但与感知到的压力无关.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
背景情况:
- 孤独是一种已知的认知能力下降和老年人健康状况不佳的风险因素,包括阿尔茨海默病患者 (AD).
- 有限的研究已经探索了孤独和感知压力的相互作用在整个认知谱的个体中,有和没有AD.
- 这项研究旨在评估老年人与不同认知状态之间的孤独和感知压力之间的关联.
研究的目的:
- 调查老年人孤独与感知压力之间的联系.
- 根据阿尔茨海默病 (AD) 症状状况,检查孤独感和感知压力的差异.
- 探索老年人孤独严重程度和认知状态之间的关系.
主要方法:
- 一项涉及136名老年人的横截面研究 (96名无症状,40名阿尔茨海默病症状).
- 参与者完成了认知测试,UCLA孤独调查和感知压力量表 (PSS).
- 使用多变量回归分析,控制年龄,性别,教育,抑郁症状和社会隔离.
主要成果:
- 大多数参与者报告中度到高水平的孤独感.
- 孤独的严重程度与阿兹海默症症状状态有显著的关联 (p=0.016),孤独的程度较高与无症状状态有关.
- 在孤独严重程度和感知压力 (p=0.10) 之间没有发现统计学意义上的关联.
结论:
- 孤独在老年人中很常见,无论他们的认知状态如何.
- 孤独的严重程度增加与阿尔茨海默病症状的不存在有显著的关联.
- 孤独和感知压力之间缺乏联系可能会突出其他因素的作用,例如社会支持.
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