公共卫生 公共卫生
Katalina F McInerney1,2, Andrew F Zaman3, Pedro R Mena2
1Department of Neurology, University of Miami Miller School of Medicine, Miami, FL, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
心血管和代谢疾病增加了西班牙裔和非裔美国人成年人的认知障碍风险. 管理这些疾病是这些社区大脑健康的关键.
科学领域:
- 神经学 神经学
- 公共卫生 公共卫生
- 老年学是一门学科.
背景情况:
- 大脑健康与心血管和代谢状况密切相关.
- 这些并发症对西班牙裔和非洲裔美国人的认知衰退的影响仍然未得到充分研究.
- 这项研究调查了社区居住的西班牙裔 (HI) 和非裔美国人 (AA) 个体中心血管和代谢问题的认知影响.
研究的目的:
- 评估心血管和代谢条件对认知的影响.
- 分析HI和AA个体的医学并发症和认知障碍之间的关系.
- 在不同的社区环境中识别认知衰退的风险因素.
主要方法:
- 分析了1908名参与者 (890名HI,1018名AA) 的队列.
- 参与者被分类为非认知障碍 (NCI) 或认知受影响 (轻度认知障碍[MCI]或阿尔茨海默病[AD]).
- 后勤回归模型检查了种族,年龄,性别,教育和心血管/代谢风险因素对认知状态的影响.
主要成果:
- 心血管和代谢风险因素的增加与认知障碍的更高可能性显著相关.
- 高龄,男性性别和西班牙裔种族也与认知障碍的风险增加有关.
- 虽然没有统计学意义,但更高的教育程度显示了对认知保护的趋势.
结论:
- 心血管和代谢条件显著提高了社区居住的HI和AA个体的认知障碍的风险.
- 观察到的风险在HI和AA组之间没有显著差异.
- 提高认识和管理这些可修改的风险因素对于预防这些人群的认知衰退至关重要.
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