公共卫生 公共卫生
Chih-Ching Liu1, Chien-Hui Liu2
1National Taipei University of Nursing and Health Sciences, No. 365, Ming-te Rd., Peitou Dist., Taipei, Taiwan.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
接种疫苗的痴呆症患者患有COVID-19感染的风险更高. 关键的风险因素包括男性,老年,低收入,居住在城市地区,并具有多种并发病.
科学领域:
- 老年学是指老年学的学科.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 在亚洲接种疫苗的痴呆症患者中,关于COVID-19风险因素的数据有限.
- 本研究的重点是确定这些风险因素在台湾.
研究的目的:
- 确定社会人口统计因素和预先存在的疾病,增加了台湾接种疫苗的痴呆症患者的COVID-19风险.
主要方法:
- 使用台湾国家健康保险研究数据库 (NHIRD) 进行的回顾性队列研究.
- 包括325,697名40岁以上的痴呆症患者.
- 分析了COVID-19疫苗接种和感染数据 (2020-2022),以及使用Cox回归的社会人口统计学和临床因素.
主要成果:
- 包括217,548名患有痴呆症的接种疫苗的参与者.
- 在男性,老年人,低收入者和城市化水平较高的人群中观察到更高的COVID-19感染风险.
- 增加的风险还与较高的查尔森并发症指数得分和特定的心理健康/慢性疾病有关.
结论:
- 接种疫苗的痴呆症患者患COVID-19的风险增加.
- 风险因素因社会人口统计和临床特征而异.
- 量身定制的公共卫生干预措施对于减轻这一群体感染风险至关重要.
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