公共卫生 公共卫生
Shanshan Wang1, Uyen-Sa Nguyen1, Zhengyang Zhou1
1University of North Texas Health Science Center, Fort Worth, TX, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
健康的社会决定因素 (SDOH) 与认知能力下降有关,包括轻度认知障碍 (MCI) 和痴呆症. 这些关联在种族和族裔群体之间存在显著差异,突出显示了需要量身定制的干预措施.
科学领域:
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
- 社会学 社会学 社会学
背景情况:
- 健康的社会决定因素 (SDOH) 显著影响健康结果.
- 认知障碍,包括轻度认知障碍 (MCI) 和痴呆症,是一个日益严重的公共卫生问题.
- 在认知健康和接触SDOH方面存在种族和种族差异.
研究的目的:
- 研究各种健康社会决定因素 (SDOH) 和认知障碍 (MCI和痴呆症) 之间的关系.
- 要确定这些关联在西班牙裔,非西班牙裔黑人和非西班牙裔白人人口中是否有所不同.
主要方法:
- 利用了来自3229名参与者的健康与衰老大脑研究-健康差异 (HABS-HD) 的数据.
- 定义了SDOH缺点的五个维度:经济,教育,医疗保健准入,社区和社会.
- 雇员多项逻辑回归,控制年龄,性别和APOE4状态.
主要成果:
- 所有五个维度的SDOH缺点都与痴呆和MCI的几率增加有关.
- 在非西班牙裔黑人个人中,SDOH缺点和痴呆症之间的关联更为强烈.
- 在非西班牙裔白人个体中,四个SDOH缺点与MCI的关联更强.
- 在SDOH缺点和认知障碍的数量之间观察到剂量反应关系.
结论:
- 广泛的SDOH与认知障碍有关.
- 与认知障碍的SDOH关联的强度因种族/族群而异.
- 需要量身定制的战略来解决SDOH和减轻认知健康差异.
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