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Updated: Jan 8, 2026

Mouse Footpad Inoculation Model to Study Viral-Induced Neuroinflammatory Responses
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基础科学和病原发生学

Daniel M Ramos1, Matthew P Nelson1, Liz Calzada1

  • 1Center for Alzheimer's and Related Dementias, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
PubMed
概括

我们开发了一种可诱导的CRISPRi系统,用于从诱导多能干细胞 (iPSC) 衍生的神经元中基因敲除. 这种工具可以发现神经元特异性疾病修饰剂和潜在的治疗点.

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