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Updated: Jan 8, 2026

Mouse Footpad Inoculation Model to Study Viral-Induced Neuroinflammatory Responses
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基础科学和病原发生学

Evelyn Pardo1, Vijay Kumar Sagar1, Kelly Kim1

  • 1University of Virginia, Charlottesville, VA, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
PubMed
概括

营养诱导的线粒体活动 (NiMA) 干扰发生在阿尔茨海默病 (AD) 发病的早期. 粉样β oligomers和APOE4表达破坏了NiMA,在AD症状出现之前影响了线粒体功能.

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