公共卫生 公共卫生
Kang Huo1, Jin Wang1, Qiumin Qu1
1The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
通过度指数 (CI) 测量较高的腹部肥胖,与成年人认知轨迹的恶化有关. 这表明中心肥胖是认知能力下降的可修改风险因素,特别是在女性和年轻人中.
科学领域:
- 老年学是一门学科.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 轻度认知障碍 (MCI) 和痴呆症对全球健康构成重大挑战.
- 由度指数 (CI) 量化的腹部肥胖与认知障碍有关.
- 关于CI对认知轨迹的影响的纵向数据有限.
研究的目的:
- 在两个不同的队列中检查度指数 (CI) 和认知轨迹之间的关联.
- 为了确定腹部肥胖是否是可改变的认知衰退风险因素.
主要方法:
- 使用西安农村居民认知队列 (XRRCC) 和美国健康与退休研究 (HRS) 数据的回顾性队列研究.
- 潜阶级增长模型 (LCGMs) 在具有正常基线认知和至少四波数据 (2014-2020) 的参与者中确定了认知轨迹.
- 多项逻辑回归分析了CI四分位数与认知轨迹之间的关联,并对共变量进行了调整.
主要成果:
- 在XRRCC (n=1,452) 中发现了两个认知轨迹 (稳定,恶化);在HRS (n=4,494) 中发现了三个 (高,中等,恶化).
- 较高的CI值与两个队列中更差的认知轨迹相关.
- 与最低四分位数相比,最高CI四分位数与认知能力下降的几率增加有关 (XRRCC:OR=0.554;HRS:OR=0.725).
结论:
- 较高的CI与较差的认知轨迹有关,特别是在女性和65岁以下的个人中.
- 腹部肥胖,以CI衡量,代表了潜在的可修改的认知恶化风险因素.
- 针对中心肥胖症的早期干预可能有助于减轻认知能力下降.
更多相关视频
09:33Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India
Published on: December 23, 2022
2.6K
07:20Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
Published on: January 28, 2014
37.1K
相关概念视频
Primary Healthcare Services
1.9K
Primary care promotes wellness and prevents disease. This care includes health promotion, education, protection (such as immunizations), early disease screening, and environmental considerations. Settings providing this type of healthcare include physician offices, public health clinics, school nursing, and community health nursing.
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
1.9K
Levels of Health Promotion and Illness Prevention
14.1K
Health promotion allows a person to control the determinants of health, resulting in an improved health status. It enhances the quality of life and reduces premature deaths. Health promotion and illness prevention programs help people make beneficial choices to reduce the risk of disease and disabilities. There are three health promotion and illness prevention levels: primary, secondary, and tertiary prevention.
In primary prevention, actions taken before disease onset prevent the disease from...
In primary prevention, actions taken before disease onset prevent the disease from...
14.1K
Preventive Healthcare Services
1.8K
Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
1.8K
Principles of Disease Surveillance
439
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
439
Healthcare Agencies II
1000
There are various healthcare agencies in the United States—some of which are managed by religious institutions and others by different government branches.
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources,...
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources,...
1000
Methods Of Healthcare Delivery System
3.9K
At the different levels of the healthcare system, we see varying methods of healthcare used. These methods include managed care systems, case management, and primary healthcare.
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...
3.9K
