公共卫生 公共卫生
Erika Cavallone1,2, Miriam T Ashford2,3, Joseph Eichenbaum2,3
1Northern California Institute for Research and Education (NCIRE), San Francisco, CA, USA.
这项研究显示了一种新方法,首先在阿尔茨海默病研究中招募研究伙伴 (SP). 这种方法有助于在临床试验中包括更多的人,甚至包括那些有认知障碍的人.
科学领域:
- 神经科学是一个神经科学.
- 临床研究 临床研究
- 老年学是一门学科.
背景情况:
- 阿尔茨海默病 (AD) 和相关痴呆症的研究通常需要研究伙伴 (SP) 的入学.
- 参与者通常是主要的接触者,可能会排除那些有认知障碍的人.
研究的目的:
- 试点测试一种新的在线注册表方法,优先考虑研究合作伙伴的招生.
- 评估"研究伙伴优先" (SP First) 招生战略在脑健康登记 (BHR) 中的可行性.
主要方法:
- 大脑健康登记 (BHR) 实施了一项新功能,允许现有参与者在没有事先邀请的情况下注册为研究合作伙伴 (SP).
- SP可以邀请关联参与者 (AP) 或作为代理人,代表AP完成评估.
- 通过跟踪邀请的AP和代理SP的入学人数和任务完成率来评估可行性.
主要成果:
- 在7个月内,1144名参与者启动了SP第一任务.
- 1,144名参与者注册了SP第一任务,其中508人提供了AP的电子邮件邀请.
- 17名相关参与者 (APs) 完成了所有评估,52名研究伙伴 (SPs) 完成了代理问卷.
结论:
- "研究伙伴优先"的方法可用于吸引和评估那些可能会被排除在研究之外的个人.
- 这种方法有助于减轻对认知障碍或低动机的老年人的选择偏见.
- 未来的扩张包括通过电子邮件邀请和社交媒体招聘进行更广泛的宣传.
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