公共卫生 公共卫生
Shilpa Srinivasan1, Charlotte Imlach2, Julie J Royer3
1Prisma Health-University of South Carolina School of Medicine Columbia, Columbia, SC, USA.
阿尔茨海默病和相关疾病 (ADRD) 在严重精神疾病 (SMI) 患者中很常见,增加了死亡率. 与其他SMI组相比,精神分裂症患者的ADRD患病率更高.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 流行病学研究表明,严重精神疾病 (SMI) 患者的认知能力下降和痴呆的风险可能更高.
- 有限的数据存在于SMI人口中痴呆的流行率,特别是在美国公共精神病学部门.
- 南卡罗来纳州阿尔茨海默氏症和相关疾病 (ADRD) 注册表为此调查提供了一个独特的资源.
研究的目的:
- 为了评估ADRD在SMI的成年人的患病率.
- 检查相关的临床结果,包括死亡率和医疗保健利用率.
- 为了比较精神分裂症患者的ADRD患病率与其他SMI诊断.
主要方法:
- 来自南卡罗来纳州精神卫生部 (SCDMH) 对55岁以上个人 (2018-2022财年) 的非身份患者数据的分析.
- 将SCDMH数据与南卡罗来纳州阿尔茨海默病登记处和税收和财政事务 (RFA) 数据仓库联系起来.
- 将SMI和ADRD个体与SMI没有ADRD的年龄/性别/种族匹配个体进行比较.
主要成果:
- 共有24,291名SMI患者接受了服务;64.8%是女性,58%是白人,37.6%是黑人.
- 在SMI人群中,每年的ADRD患病率在9.7-17%之间.
- 与其他SMI诊断相比,精神分裂症患者的阿尔茨海默氏症 (AD) 患病率显著更高 (p < 0.0001).
- 与SMI相比,SMI和ADRD患者的死亡率明显高于仅SMI患者 (p < 0.0001).
结论:
- 阿尔茨海默病和相关疾病在SMI患者中普遍存在,并与死亡率增加有关.
- 在被诊断为精神分裂症的个体中,ADRD比其他SMI的个体更常见.
- 这些发现强调需要在SMI人群中进一步研究ADRD,以告知患者护理和服务提供.
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