公共卫生 公共卫生
Marissa D Zwan1,2, Kay Deckers3, Lisa Waterink1,2
1Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, Netherlands.
FINGER-NL研究正在评估荷兰老年人面临认知能力下降风险的多领域生活方式干预措施. 值得注意的是,参与者的坚持度很高,他们热衷于延长随访,以评估长期的认知健康.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 该FINGER-NL研究调查了为期2年的多领域生活方式干预.
- 它的目标是荷兰的老年人面临认知能力下降的风险.
- 本研究提供了关于其进展和后续行动的最新情况.
研究的目的:
- 评估多领域生活方式干预措施的有效性.
- 在高危老年人中保持最佳的认知功能.
- 提供关于FINGER-NL研究进展和后续行动的最新情况.
主要方法:
- 一个为期24个月,多中心,随机对照试验 (RCT) 在世界范围的手指倡议.
- 纳入标准:60-80岁,具有可修改的 (LIBRA评分) 和不可修改的认知衰退风险因素.
- 随机化为高强度 (个性化,监督混合方案) 或低强度 (数字信息) 的生活方式干预.
主要成果:
- 在2022年2月至2023年5月期间,有1210名符合条件的个人被随机选择 (605名高强度,605名低强度).
- 一年后的随访完成了90% (高强度) 和83% (低强度) 的参与者.
- 目前正在进行为期两年的随访;74%的受访者同意进行为期3-4年的延期研究.
结论:
- 芬格-NL正在取得良好进展,正在进行数据收集和计划进行生物标志物分析.
- 参与者坚持,特别是在低强度组,需要注意.
- 显而易见的是,参与者对延长后续和数据共享机会的高度兴趣.
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