公共卫生 公共卫生
Yujiro Kuroda1,2, Kazuaki Uchida1, Yoko Yokoyama1
1National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
一个多领域的痴呆症预防计划在两个城市中显示出可行性和接受性. 该计划包括运动,营养和认知训练,显示出积极的结果和适应性,可用于社区实施.
科学领域:
- 老年学与公共卫生
- 神经科学与认知衰老
背景情况:
- 预防痴呆症是一个重大的公共卫生挑战,需要创新的社区干预措施.
- 一个综合运动,营养,认知训练,社会参与和血管风险管理的多领域计划进行了试点测试.
研究的目的:
- 在两个不同的社区环境中评估多领域痴呆症预防计划的可行性和可接受性.
- 根据试点发现和当地需求调整干预措施,包括教师培训和参与者招生策略.
主要方法:
- 在O City的一项单臂试验 (n=80,65-86岁) 评估了一项为期12个月的计划,通过≥60%的出席率来定义可行性.
- 在H镇实施了经过修订的6个月基本+6个月延续计划,并采用了结构化招生协议.
- 评估了认知功能 (MoCA-J) 和食物多样性;测量了参与者的接受度和继续工作的意愿.
主要成果:
- 在O城,75%的人符合出席标准,接受度高 (4.4/5);认知分数保持稳定,食物多样性显著改善 (p=0.008).
- 在H镇,修订后的计划招收了19名参与者,超过70%的人表示愿意继续参与.
- 该计划在不同的实施模式和社区环境中展示了适应性.
结论:
- 多领域痴呆症预防计划在社区环境中是可行的和可接受的,可以适应当地需求和做法.
- 结果支持该计划对更广泛社区影响的潜力,未来需要进行受控研究来确认认知和健康益处.
- 精细的招聘和后续策略对于扩大痴呆症预防计划至关重要.
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