公共卫生 公共卫生
Lily Kamalyan1, Sara E Walker1, Alicia R Pacheco1
1Columbia University Medical Center, New York, NY, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
痴呆症家族史 (FHD) 在中年拉丁裔成年人中对双语或移民身份的认知没有产生不同影响. 移民身份,而不是FHD,与这个群体的认知功能较差有关.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
- 公共卫生 公共卫生
背景情况:
- 痴呆症家族史 (FHD) 是认知能力下降的已知风险因素.
- 拉丁裔人口面临患阿尔茨海默病和相关痴呆症 (ADRD) 的风险更高.
- 双语可能提供认知方面的好处,但往往与移民身份和测试语言交织在一起.
研究的目的:
- 调查双语,移民身份和测试语言是否会缓和家族痴呆史 (FHD) 与认知功能之间的关联.
- 确定中年拉丁裔人口中痴呆风险和保护因素.
主要方法:
- 1,121名中年拉丁裔成年人接受了神经心理评估.
- 参与者根据移民身份和双语 (单语移民/西班牙语,双语移民/西班牙语,双语移民/英语,双语美国出生的/英语) 进行分类.
- 多个线性模型分析了FHD和认知领域之间的关联,控制了人口因素.
主要成果:
- 痴呆症家族史 (FHD) 仅与更糟糕的记忆有关.
- 双语与处理速度正相关.
- 移民状况对记忆,语言和处理速度产生了负面影响,对FHD-认知关系没有缓解作用.
结论:
- 双语和移民身份独立地影响中年拉丁裔成年人的认知功能.
- 移民状况与认知领域的负面关联比FHD或双语更强.
- 进一步的研究应该探索双语和移民的细微方面,以更好地预测ADRD风险.
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