公共卫生 公共卫生
Elizabeth Muñoz1, Lourdes S Romañach Álvarez1, Jean Choi1
1University of Texas at Austin, Austin, TX, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
早期和中年生活中的邻居不利影响认知功能,特别是处理速度和空间能力. 早期生活和当前社区环境对于理解认知健康轨迹至关重要.
科学领域:
- 环境健康 环境健康
- 认知神经科学是一种认知神经科学.
- 寿命心理学 寿命心理学
背景情况:
- 生活过程中的环境背景显著影响认知功能.
- 早期和中年期间的邻居不利情况可能会损害认知能力.
- 微妙的中年认知变化可以预示早期神经认知障碍.
研究的目的:
- 检查早期生活和与特定的中年认知能力并发的邻里劣势之间的独立和联合关联.
- 调查社区贫困如何影响整个生命周期的认知功能.
主要方法:
- 利用了来自1,141名CATSLife参与者的数据,其中包括从婴儿期到中年早期的地址数据.
- 地理编码地址并与人口普查数据链接,以计算早期和当前时期的区域贫困指数 (ADI).
- 使用通用估计方程来评估ADI对认知能力 (语言,记忆,空间,处理速度) 的影响,控制共变量.
主要成果:
- 早期生活和当前邻居的劣势独立地与较差的处理速度有关.
- 当前的邻居劣势与较低的空间功能有关,独立于早期的生活条件.
- 没有发现对记忆或语言能力的显著关联,也没有发现早期生活和当前ADI之间的显著相互作用.
结论:
- 早期生活和当前社区剥夺都与减少处理速度独立相关.
- 当前的社区贫困独特地预测了空间功能较差,突出显示了持续环境暴露的重要性.
- 研究结果强调需要考虑对认知轨迹的累积和并发邻近效应.
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